Altered redox signaling contributes to CCM pathogenesis



A recent research work published in Scientific Reports and supported by the Telethon Foundation demonstrate that altered redox signaling is a major contributor to increased endothelial permeability in experimental models of CCM disease, thus confirming and extending previous reports suggesting that oxidative stress plays an important role in CCM pathogenesis and severity.
Sci Rep. 2017 Aug 15;7(1):8296.
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